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Brintellix Review

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Brintellix is a prescription only medication used to treat major depressive disorder in adults. In short term studies, it has been shown to improve the symptoms of depression within the first four weeks of use.

It is not known how the medication works exactly, but it is thought to increase the serotonin activity in the brain.



Brintellix is made up of several ingredients. The main active ingredient in Brintellix is vortioxetine hydrobromide.

There are many inactive ingredients in the medication and they include mannitol, microcrystalline cellulose, hydroxypropyl cellulose, sodium starch glycolate, magnesium stearate and film coating which consists of hypromellose, titanium dioxide, polyethylene glycol 400, iron oxide red, which is a coloring agent and found in the 5 mg, 15 mg, and 20 mg tablets, and iron oxide yellow which is found in the10 mg and 15 mg tablets.


It is recommended that patients begin taking Brintellix at 10 mg once per day. After several days doctors may increase the medication to 20 mg per day. However, doses above 20 mg have not been tested in clinical trials for its effectiveness.

Possible Side Effects

The most common side effects are:

  • Nausea
  • Constipation
  • Vomiting

Patients in clinical studies reported that nausea increased or decreased in relation to the dosage of the medication.

There may be other side effects associated with this medication not listed here.

Will This Product Produce Long-Term Results?

Brintellix is designed for long-term treatment of major depression. Unlike with some other prescription medications, patients can stop using Brintellix at any time.


Brintellix is a very expensive prescription medication with a cost of over $250. This high price may be out of many patients’ budgets. There is a link on their website to apply for financial assistance.


Brintellix is a prescription medication; therefore it does not come with any money-back guarantee.

However you can report unwanted side effects or other issues to the FDA. The FDA has established a reporting service called MedWatch. Health care professionals and consumers can call to report any problems they believe may be related to the prescription medication they are using by calling 1-800-FDA-1088.


Brintellix is a very expensive prescription medication. Although it may not have a long list of side effects like other prescription medications, there are other options available.

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